WebNov 11, 2024 · Paclitaxel is a chemotherapeutic agent that acts as an inhibitor of cellular mitosis and has been widely used in the treatment of triple-negative breast cancer … WebAug 4, 2024 · Circular RNAs (circRNAs) and epithelial to mesenchymal transition (EMT) have been implicated in the development of human cancer and paclitaxel resistance. CircRNA circ_0007534 has been described as a key oncogenic circular RNA that is upregulated in a variety of cancer tissues. However, whether circ_0007534 causes EMT …
Paclitaxel (Conventional) - Drugs.com
WebApr 11, 2024 · BackgroundThere are a variety of treatment options for recurrent platinum-resistant ovarian cancer, and the optimal specific treatment still remains to be determined. Therefore, this Bayesian network meta-analysis was conducted to investigate the optimal treatment options for recurrent platinum-resistant ovarian cancer.MethodsPubmed, … WebPaclitaxel (PTX) is a first-line drug for late-stage non-small cell lung cancer (NSCLC) patients who do not benefit from targeted therapy or immunotherapy. However, patients invariably develop resistance to PTX upon prolonged treatments. Although diverse mechanisms leading to PTX resistance have bee … load testing bridges
New insight towards development of paclitaxel and docetaxel …
WebIntroduction. Breast cancer (BC) remains the most common type of cancer among women. 1 Paclitaxel (PTX), a type of chemotherapeutic drug taxanes, is an antineoplastic drug, which induces cell death by impacting microtubule stabilization. 2 PTX has been clinically approved and used for BC treatment and is effective against early and metastatic BC. 3 … WebNov 19, 2010 · The chemical name of paclitaxel is 5β, 20-epoxy-1,2α,4, 7β,10β,13α-hexahydroxytax-11-en-9-one4, 10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine. The chemical formula of paclitaxel is C47H51O14, with a molecular weight of 853.9. It is highly lipophilic, insoluble in water, and melts at 217°C. WebDec 21, 2024 · Warning. This medicine may lower the ability of the bone marrow to make blood cells that the body needs. If blood cell counts get very low, this can lead to … indiana house bill 1001