WebApr 30, 2015 · For example, the LC8 family members of dynein light chains have been shown to interact, besides dynein, with a large number of proteins. 18 Similarly, the Tctex family member of Tctex-1 (or DYNLT1) has dynein-independent roles in actin remodeling during neurite outgrowth 19 and in ciliary resorption. 20,21 We now show that Tctex-1 … WebMar 7, 2002 · The interactions of three subunits of cytoplasmic dynein from Drosophila melanogaster, LC8, Tctex-1, and the N-terminal domain of IC74 (N-IC74, residues …
6993 - Gene ResultDYNLT1 dynein light chain Tctex-type 1
WebThe external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. WebJul 1, 2024 · Objective: To investigate dynein light chain Tctex-type 3 (DYNLT3) protein expression in ovarian epithelial lesions and explore the effects and related mechanisms of DYNLT3 in terms of the biological behavior of ovarian cancer. Materials and methods: Initially, expression of the DYNLT3 protein in ovarian epithelial lesions was detected by … ray birdwhistell aportes
Ting-Yu Yeh - Co-Founder and Chief Scientific Officer
DYNLT1 (Dynein Light Chain Tctex-Type 1) is a Protein Coding gene. Diseases associated with DYNLT1 include Glaucomatocyclitic Crisis and Pulmonary Hypertension . Among its related pathways are Innate Immune System and Regulation of degradation of deltaF508 CFTR in CF . WebJun 10, 2005 · TcTex-1, one of three dynein light chains of the dynein motor complex, has been implicated in targeting and binding cargoes to cytoplasmic dynein for retrograde or apical transport. Interactions between TcTex-1 and a diverse set of proteins such as the dynein intermediate chain, Fyn, DOC2, FIP1, the poliovirus receptor, CD155, and the … WebMar 7, 2002 · The interactions of three subunits of cytoplasmic dynein from Drosophila melanogaster, LC8, Tctex-1, and the N-terminal domain of IC74 (N-IC74, residues 1−289), were characterized in vitro by affinity methods, limited proteolysis, and circular dichroism spectroscopy. These subunits were chosen for study because they are presumed to … ray birch tucson az